HDL or good cholesterol can be life threatening, says a new study

Contrary to claims that good cholesterol is beneficial to the heart, a new study has showed that very high levels may be associated with an increased risk of heart attack and death.

The findings showed that people with high-density lipoprotein (HDL or good) cholesterol levels of 41-60 mg/dl (milligrams per decilitre) had the lowest risk of heart attack or cardiovascular death.

However, the risk increased in people with low levels (less than 41 mg/dl) as well as very high levels (greater than 60 mg/dl) of HDL cholesterol.

People with HDL cholesterol levels greater than 60 mg/dl had a nearly 50 per cent increased risk of dying from a cardiovascular cause or having a heart attack compared to those with HDL cholesterol levels 41-60 mg/dl.

“It may be time to change the way we view HDL cholesterol. Traditionally, physicians have told their patients that the higher your ‘good’ cholesterol, the better,” said Marc Allard-Ratick, from the Emory University in Atlanta, US.

“However, the results from this study and others suggest that this may no longer be the case,” he added.

The bad effects of very high HDL cholesterol were consistent even after controlling other risk factors for heart disease such as diabetes, smoking, and low-density lipoprotein (LDL or bad) cholesterol, as well as other factors such as alcohol intake, race, and sex.

HDL cholesterol has been considered “good” because the HDL molecule is involved in the transport of cholesterol from the blood and blood vessel walls to the liver and ultimately out of the

body, thereby reducing the risk of clogged arteries and atherosclerosis, the researchers explained.

The study investigated the relationship between HDL cholesterol levels and the risk of heart attack and death in 5,965 individuals, most of whom had heart disease.

The results were presented at the ESC Congress 2018, the annual conference of the European Society of Cardiology in Munich, Germany.

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Low muscle strength linked to premature death, says study

Individuals with weaker muscles do not typically live as long as their stronger peers, and are 50 per cent more likely to die earlier, finds a study.

According to researchers, muscle strength may be an even more important predictor of overall health and longevity than muscle mass.

In addition, hand grip strength specifically has been found to be inversely related to mobility limitations and disability.

However, despite being a relatively simple and cost-effective test, grip strength measurement is not currently part of most routine physicals, they said.

“Maintaining muscle strength throughout life-and especially in later life-is extremely important for longevity and ageing independently,” said lead researcher Kate Duchowny, post-doctoral student at the University of California-San Francisco.

The study, published in the Journal of Gerontology: Medical Sciences, highlights the importance of integrating grip strength measurements into routine care-not just for older adults but even in midlife.

“Having hand grip strength be an integral part of routine care would allow for earlier interventions, which could lead to increased longevity and independence for individuals,” Duchowny said.

For the study, the team analysed data of 8,326 men and women, aged 65 and older.

After adjusting for socio-demographic factors, chronic health conditions and smoking history, the results showed that people with low muscle strength are 50 per cent more likely to die earlier.

[“source=indiatvnews”]